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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181071Generated: November 1, 2026

3-[4-Hydroxy-2-(isopropoxycarbonylamino-methyl)-phenyl]-propionic acid tert-butyl ester → 3-(2-(Isopropoxycarbonylamino-methyl)-4-{2-[5-methyl-2-(4-nitro-phenyl)-oxazol-4-yl]-ethoxy}-phenyl)-propionic acid tert-butyl ester

https://huagongshe.com/reaction/1181071

Reaction equation

Participants

RoleNameHCIDCharge
Reactant3-[4-Hydroxy-2-(isopropoxycarbonylamino-methyl)-phenyl]-propionic acid tert-butyl esterHCID 58979470—
Reactant4-Methyl-3-nitro-benzenesulfonic acid 2-[5-methyl-2-(4-nitro-phenyl)-oxazol-4-yl]-ethyl esterHCID 58979495—
Product3-(2-(Isopropoxycarbonylamino-methyl)-4-{2-[5-methyl-2-(4-nitro-phenyl)-oxazol-4-yl]-ethoxy}-phenyl)-propionic acid tert-butyl esterHCID 58979358—

Reaction Steps

4-Methyl-3-nitro-benzenesulfonic acid 2-[5-methyl-2-(4-nitro-phenyl)-oxazol-4-yl]-ethyl ester (Preparation 7) and 3-[4-hydroxy-2-(isopropoxycarbonylamino-methyl)-phenyl]-propionic acid tert-butyl ester were coupled by Standard procedure A to give the title compound.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07282501B2
Source datasetuspto-grants-2007_10
ORD IDord-c547cf59481e489e993c50805e0d2c91
Source noteuspto-grants-2007_10