反应详情

温度

100 °C

Adenine (1 mmol) in DMF was treated with sodium hydride (1.2 mmol) followed by benzyl bromide (1.2 mmol) at room temperature under nitrogen. The resulting mixture was warmed at 100° C. for 2 h. The cooled reaction mixture was evaporated to dryness. Extraction and chromatography afforded N9-benzyladenine.

1. customThe cooled reaction mixture
2. customwas evaporated to dryness
3. extractionExtraction and chromatography