関与物質
| 役割 | 名称 | HCID | 仕込み量 |
|---|
| 反応物 | Adenine | HCID 190 | — |
| 反応物 | Benzyl Bromide | HCID 7498 | — |
| 反応物 | Sodium hydride | HCID 24758 | — |
| 溶媒 | Dimethylformamide | HCID 6228 | — |
| 生成物 | 9-(Phenylmethyl)-9H-purin-6-amine | HCID 20262 | — |
反応手順
Adenine (1 mmol) in DMF was treated with sodium hydride (1.2 mmol) followed by benzyl bromide (1.2 mmol) at room temperature under nitrogen. The resulting mixture was warmed at 100° C. for 2 h. The cooled reaction mixture was evaporated to dryness. Extraction and chromatography afforded N9-benzyladenine.
情報源と証拠
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 特許番号 | US07285543B2 |
|---|
| 出典データセット | uspto-grants-2007_10 |
|---|
| ORD ID | ord-a631dcfe8f3941e3912af92044a6d41c |
|---|
| 出典メモ | uspto-grants-2007_10 |
|---|
