Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | Sodium Hydroxide | HCID 14798 | — |
| Reactant | 9-Benzyl-8-bromoadenine | HCID 9904551 | — |
| Reactant | HCID 23421211 | HCID 23421211 | — |
| Solvent | Water ethanol | HCID 19096565 | — |
| Product | HCID 42637648 | HCID 42637648 | — |
Reaction Steps
A mixture of N9-benzyl-8-bromoadenine (1 mmol), aminoethylphosphonate (2 mmol), and sodium hydroxide (2 mmol) in ethanol-water in a sealed tube was warmed at 110° C. under nitrogen. After 24 h the cooled reaction mixture was purified through preparative HPLC to give N9-benzyl-8-(2-phosphonoethylamino)adenine (3.1). Exact mass calculated for C14H17N6O3P+H+: 349.1178. Found: 349.1180.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| Patent number | US07285543B2 |
|---|
| Source dataset | uspto-grants-2007_10 |
|---|
| ORD ID | ord-f4ee8d3398ac4bba899695796004d590 |
|---|
| Source note | uspto-grants-2007_10 |
|---|
