HuagongsheHuagongshe Chemistry Print Report · For research reference only
Ammonia → HCID 86602092, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Ammonia | HCID 222 | — |
| Reactant | HCID 86602093 | HCID 86602093 | — |
| Solvent | dimethylsulfoxide THF | HCID 21830753 | — |
| Product | HCID 86602092 | HCID 86602092 | — |
Reaction Steps
A solution of 6-chloro-8-diethylphosphonomethoxymethyl-N9-neopentylpurine (1 mmol) in THF-DMSO was treated with liquid ammonia (10 mmol) at 25° C. for 6 h. Extraction and chromatography afforded 8-diethylphosphonomethoxymethyl-N9-neopentyladenine as a white solid. TLC: Rf=0.44, 25% MeOH-EtOAc.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07285543B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-7698d40eb0cd48f3aa5c7c6aa72275a0 |
| Source note | uspto-grants-2007_10 |