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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181447Generated: October 26, 2026

Cinnolin-5-amine → N-Cinnolin-5-yl-N'-[4-(trifluoromethyl)benzyl]urea

https://huagongshe.com/reaction/1181447

Reaction equation

Participants

RoleNameHCIDCharge
ReactantCinnolin-5-amineHCID 387103—
Reactant4-(Trifluoromethyl)benzyl isocyanateHCID 22337699—
ProductN-Cinnolin-5-yl-N'-[4-(trifluoromethyl)benzyl]ureaHCID 69523120—

Reaction Steps

Prepared from cinnolin-5-amine (Sci Pharm. 1982, 50, 246) and [4-(trifluoromethyl)benzyl]isocyanate (Description 58) according to the procedure of Description 61. m/z (ES+) 347 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285563B2
Source datasetuspto-grants-2007_10
ORD IDord-62b79cc006ba4d1387f8bc5b847e6732
Source noteuspto-grants-2007_10