1-Methylisoquinolin-5-amine → N-(1-Methylisoquinolin-5-yl)-N'-[4-(trifluoromethoxy)benzyl]urea

HRID 1181475노트

반응식

HRID 1181475 반응식
[CH3:1][C:2]1[C:11]2[CH:10]=[CH:9][CH:8]=[C:7]([NH2:12])[C:6]=2[CH:5]=[CH:4][N:3]=1.[F:13][C:14]([F:27])([F:26])[O:15][C:16]1[CH:25]=[CH:24][C:19]([CH2:20][N:21]=[C:22]=[O:23])=[CH:18][CH:17]=1>>[CH3:1][C:2]1[C:11]2[C:6](=[C:7]([NH:12][C:22]([NH:21][CH2:20][C:19]3[CH:18]=[CH:17][C:16]([O:15][C:14]([F:13])([F:27])[F:26])=[CH:25][CH:24]=3)=[O:23])[CH:8]=[CH:9][CH:10]=2)[CH:5]=[CH:4][N:3]=1

참가 물질

3

반응물 2

HCID 99894901-Methylisoquinolin-5-amineHCID 156751741-(Isocyanatomethyl)-4-(trifluoromethoxy)benzene

생성물 1

HCID 69522602N-(1-Methylisoquinolin-5-yl)-N'-[4-(trifluoromethoxy)benzyl]urea

실험 절차

Prepared from 1-methylisoquinolin-5-amine (Description 68) and [4-(trifluoromethoxy)benzyl]isocyanate (Description 59) according to the procedure of Description 61. m/z (ES+) 376 (M+H)+.

출처 및 근거

ORD 기록
ord-efd2deaf11ee49de9988c2c9358652af
출처 데이터셋
uspto-grants-2007_10
특허 번호
US07285563B2

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