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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181475Generated: October 26, 2026

1-Methylisoquinolin-5-amine → N-(1-Methylisoquinolin-5-yl)-N'-[4-(trifluoromethoxy)benzyl]urea

https://huagongshe.com/reaction/1181475

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methylisoquinolin-5-amineHCID 9989490—
Reactant1-(Isocyanatomethyl)-4-(trifluoromethoxy)benzeneHCID 15675174—
ProductN-(1-Methylisoquinolin-5-yl)-N'-[4-(trifluoromethoxy)benzyl]ureaHCID 69522602—

Reaction Steps

Prepared from 1-methylisoquinolin-5-amine (Description 68) and [4-(trifluoromethoxy)benzyl]isocyanate (Description 59) according to the procedure of Description 61. m/z (ES+) 376 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285563B2
Source datasetuspto-grants-2007_10
ORD IDord-efd2deaf11ee49de9988c2c9358652af
Source noteuspto-grants-2007_10