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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181478Generated: October 26, 2026

4-(Trifluoromethyl)benzyl isocyanate → N-(8-Fluoro-3-methylisoquinolin-5-yl)-N'-[4-(trifluoromethyl)benzyl]urea

https://huagongshe.com/reaction/1181478

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)benzyl isocyanateHCID 22337699—
Reactant8-Fluoro-3-methylisoquinolin-5-amineHCID 69159363—
ProductN-(8-Fluoro-3-methylisoquinolin-5-yl)-N'-[4-(trifluoromethyl)benzyl]ureaHCID 69522967—

Reaction Steps

Prepared from 8-fluoro-3-methylisoquinolin-5-amine (Description 76) and [4-(trifluoromethyl)benzyl]isocyanate (Description 58) according to Description 61. m/z (ES+) 378 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285563B2
Source datasetuspto-grants-2007_10
ORD IDord-8baa34b07c034615b6d1dbd4b0758929
Source noteuspto-grants-2007_10