Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181485Generated: October 27, 2026

4-(Trifluoromethyl)benzyl isocyanate → N-(6-Fluoroisoquinolin-5-yl)-N'-[4-(trifluoromethyl)benzyl]urea

https://huagongshe.com/reaction/1181485

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)benzyl isocyanateHCID 22337699—
Reactant6-Fluoroisoquinolin-5-amineHCID 45090762—
ProductN-(6-Fluoroisoquinolin-5-yl)-N'-[4-(trifluoromethyl)benzyl]ureaHCID 69522782—

Reaction Steps

Prepared from 6-fluoroisoquinolin-5-amine (Description 89) and [4-(trifluoromethyl)benzyl]isocyanate (Description 58) according to Description 61. m/z (ES+) 364 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285563B2
Source datasetuspto-grants-2007_10
ORD IDord-7177b8e7db814409a203e39027ae342d
Source noteuspto-grants-2007_10