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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181491Generated: November 2, 2026

4-(Trifluoromethyl)benzyl isocyanate → N-[7-(trifluoromethyl)isoquinolin-5-yl]-N'-[4-(trifluoromethyl)benzyl]urea

https://huagongshe.com/reaction/1181491

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(Trifluoromethyl)benzyl isocyanateHCID 22337699—
Reactant7-(Trifluoromethyl)isoquinolin-5-amineHCID 69522391—
ProductN-[7-(trifluoromethyl)isoquinolin-5-yl]-N'-[4-(trifluoromethyl)benzyl]ureaHCID 86598046—

Reaction Steps

Prepared from 7-(trifluoromethyl)isoquinolin-5-amine (Description 99) and [4-(trifluoromethyl)benzyl]isocyanate (Description 58) according to Description 61. m/z (ES+) 414 (M+H)+.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285563B2
Source datasetuspto-grants-2007_10
ORD IDord-7ceba74fb2bc4069919de583aebe5cfc
Source noteuspto-grants-2007_10