HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-(Chloromethyl)pyridinium chloride → 7-isobutyl-2-(1-naphthylmethyl)-3-pyridin-4-yl-5-(pyridin-4-ylmethyl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-(Chloromethyl)pyridinium chloride | HCID 74570 | — |
| Reactant | 1,8-Diazabicyclo(5.4.0)undec-7-ene | HCID 81184 | — |
| Reactant | 7-isobutyl-2-(1-naphthylmethyl)-3-pyridin-4-yl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione | HCID 69427445 | — |
| Product | 7-isobutyl-2-(1-naphthylmethyl)-3-pyridin-4-yl-5-(pyridin-4-ylmethyl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione | HCID 58981012 | — |
Reaction Steps
This compound was synthesized by the reaction of 7-isobutyl-2-(1-naphthylmethyl)-3-pyridin-4-yl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione and 4-(chloromethyl)pyridine hydrochloride using DBU as a base. Mass: 516.88 (M+H).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07285558B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-173de81ff3b246fc9625e322eba0a7fc |
| Source note | uspto-grants-2007_10 |