Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181766Generated: October 25, 2026

1-Methyl-2-imidazolecarboxaldehyde → 2-[(5-chloro-1H-indol-3-yl)methyl]-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

https://huagongshe.com/reaction/1181766

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-2-imidazolecarboxaldehydeHCID 139575—
Reactant5-chloro-1H-indole-3-carbaldehydeHCID 2795374—
Reactant6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dioneHCID 11378629—
Product2-[(5-chloro-1H-indol-3-yl)methyl]-5-methyl-3-(1-methyl-1H-imidazol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dioneHCID 136334114—

Reaction Steps

This compound was made following the procedure described above, starting with 6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 5-chloro-1H-indole-3-carbaldehyde, followed by 1-methyl-1H-imidazole-2-carbaldehyde

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285558B2
Source datasetuspto-grants-2007_10
ORD IDord-b979ddfa963446599daff7ea298a6a37
Source noteuspto-grants-2007_10