Potassium Carbonate → 7-[(3,5-dimethylisoxazol-4-yl)methyl]-5-methyl-2-(1-naphthylmethyl)-3-pyridin-4-yl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Participants

Role	Name	HCID	Charge
Reactant	Potassium Carbonate	HCID 11430	—
Reactant	4-(Bromomethyl)-3,5-dimethyl-1,2-oxazole	HCID 12793289	—
Reactant	5-methyl-2-(1-naphthylmethyl)-3-(4-pyridinyl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione	HCID 136334113	—
Solvent	Dimethylformamide	HCID 6228	—
Product	7-[(3,5-dimethylisoxazol-4-yl)methyl]-5-methyl-2-(1-naphthylmethyl)-3-pyridin-4-yl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione	HCID 58981037	—

Reaction Steps

This compound was synthesized by the reaction of 5-methyl-2-(1-naphthylmethyl)-3-pyridin-4-yl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione and 4-(bromomethyl)-3,5-dimethylisoxazole using potassium carbonate as abase in DMF at 80° C. Mass: 492.94 (M+H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07285558B2
Source dataset	uspto-grants-2007_10
ORD ID	ord-c2441fd4f09c4b368afee10630cf305c
Source note	uspto-grants-2007_10