HRID1181772

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID11430

Potassium Carbonate

CK2O3

HCID12793289

4-(Bromomethyl)-3,5-dimethyl-1,2-oxazole

C6H8BrNO

结构：Cn1c(=O)[nH]c2nn(Cc3cccc4ccccc34)c(-c3ccncc3)c2c1=O

HCID136334113

未命名化合物

PRODUCTS

生成物

结构：Cc1noc(C)c1Cn1c(=O)n(C)c(=O)c2c(-c3ccncc3)n(Cc3cccc4ccccc34)nc21

HCID58981037

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

溶剂HCID6228

N,N-Dimethylformamide

C3H7NO

PROCEDURE

实验过程

This compound was synthesized by the reaction of 5-methyl-2-(1-naphthylmethyl)-3-pyridin-4-yl-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione and 4-(bromomethyl)-3,5-dimethylisoxazole using potassium carbonate as abase in DMF at 80° C. Mass: 492.94 (M+H).

WORKUP

后处理

customat 80° C

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c2441fd4f09c4b368afee10630cf305c
来源数据集: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07285558B2
来源说明: uspto-grants-2007_10

反应 SMILES

[CH3:1][N:2]1[C:7](=[O:8])[C:6]2=[C:9]([C:23]3[CH:28]=[CH:27][N:26]=[CH:25][CH:24]=3)[N:10]([CH2:12][C:13]3[C:22]4[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=4)[CH:16]=[CH:15][CH:14]=3)[N:11]=[C:5]2[NH:4][C:3]1=[O:29].Br[CH2:31][C:32]1[C:33]([CH3:38])=[N:34][O:35][C:36]=1[CH3:37].C(=O)([O-])[O-].[K+].[K+]>CN(C=O)C>[CH3:38][C:33]1[C:32]([CH2:31][N:4]2[C:5]3=[N:11][N:10]([CH2:12][C:13]4[C:22]5[C:17](=[CH:18][CH:19]=[CH:20][CH:21]=5)[CH:16]=[CH:15][CH:14]=4)[C:9]([C:23]4[CH:24]=[CH:25][N:26]=[CH:27][CH:28]=4)=[C:6]3[C:7](=[O:8])[N:2]([CH3:1])[C:3]2=[O:29])=[C:36]([CH3:37])[O:35][N:34]=1