HRID1181779

反应详情

EQUATION

反应方程式

REACTANTS

反应物

HCID227328

1-benzothiophene-3-carbaldehyde

C9H6OS

HCID11629963

未命名化合物

HCID19356084

未命名化合物

PRODUCTS

生成物

结构：CC(C)Cn1c(=O)n(C)c(=O)c2c(-c3nc(NC(=O)OC(C)(C)C)cn3C)n(Cc3csc4ccccc34)nc21

HCID69431750

未命名化合物

PROCEDURE

实验过程

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 1-benzothiophene-3-carbaldehyde, followed by tert-butyl 2-formyl-1-methyl-1H-imidazol-4-ylcarbamate.

来源与证据

来源类型: Open Reaction Database
ORD 记录: ord-c7462cf178664e1785802959430b906b
来源数据集: uspto-grants-2007_10
DOI: 10.6084/m9.figshare.5104873.v1
专利: US07285558B2
来源说明: uspto-grants-2007_10

反应 SMILES

[NH:1]([C:3]1[N:8]([CH2:9][CH:10]([CH3:12])[CH3:11])[C:7](=[O:13])[N:6]([CH3:14])[C:5](=[O:15])[CH:4]=1)[NH2:2].[S:16]1[C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=2[C:18]([CH:25]=O)=[CH:17]1.[CH:27]([C:29]1[N:30]([CH3:42])[CH:31]=[C:32]([NH:34][C:35](=[O:41])[O:36][C:37]([CH3:40])([CH3:39])[CH3:38])[N:33]=1)=O>>[S:16]1[C:20]2[CH:21]=[CH:22][CH:23]=[CH:24][C:19]=2[C:18]([CH2:25][N:2]2[C:27]([C:29]3[N:30]([CH3:42])[CH:31]=[C:32]([NH:34][C:35](=[O:41])[O:36][C:37]([CH3:38])([CH3:40])[CH3:39])[N:33]=3)=[C:4]3[C:3]([N:8]([CH2:9][CH:10]([CH3:11])[CH3:12])[C:7](=[O:13])[N:6]([CH3:14])[C:5]3=[O:15])=[N:1]2)=[CH:17]1