1-Benzothiophene-3-carbaldehyde → tert-butyl 2-[2-(1-benzothien-3-ylmethyl)-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-imidazol-4-ylcarbamate

Participants

Role	Name	HCID	Charge
Reactant	1-Benzothiophene-3-carbaldehyde	HCID 227328	—
Reactant	tert-butyl N-(2-formyl-1-methyl-1H-imidazol-4-yl)carbamate	HCID 11629963	—
Reactant	6-hydrazino-1-isobutyl-3-methyl-2,4(1H,3H)-pyrimidinedione	HCID 19356084	—
Product	tert-butyl 2-[2-(1-benzothien-3-ylmethyl)-7-isobutyl-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]-1-methyl-1H-imidazol-4-ylcarbamate	HCID 69431750	—

Reaction Steps

This compound was made following the procedure described above, starting with 6-hydrazino-1-isobutyl-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 1-benzothiophene-3-carbaldehyde, followed by tert-butyl 2-formyl-1-methyl-1H-imidazol-4-ylcarbamate.

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07285558B2
Source dataset	uspto-grants-2007_10
ORD ID	ord-c7462cf178664e1785802959430b906b
Source note	uspto-grants-2007_10