Trifluoroacetic acid → HCID 58980940, compound

HRID 1181787Notes

Reaction equation

HRID 1181787 reaction equation
[Cl:1][C:2]1[CH:3]=[C:4]2[C:9](=[CH:10][CH:11]=1)[N:8]=[CH:7][CH:6]=[C:5]2[CH2:12][N:13]1[C:21]([C:22]2[S:26][C:25]([NH:27]C(=O)OC(C)(C)C)=[N:24][C:23]=2[CH3:35])=[C:20]2[C:15]([N:16]([CH2:39][CH:40]3[CH2:42][CH2:41]3)[C:17](=[O:38])[N:18]([CH3:37])[C:19]2=[O:36])=[N:14]1.C(O)(C(F)(F)F)=O>ClCCl>[NH2:27][C:25]1[S:26][C:22]([C:21]2[N:13]([CH2:12][C:5]3[C:4]4[C:9](=[CH:10][CH:11]=[C:2]([Cl:1])[CH:3]=4)[N:8]=[CH:7][CH:6]=3)[N:14]=[C:15]3[C:20]=2[C:19](=[O:36])[N:18]([CH3:37])[C:17](=[O:38])[N:16]3[CH2:39][CH:40]2[CH2:42][CH2:41]2)=[C:23]([CH3:35])[N:24]=1

Participants

4

Reactant 2

HCID 6422Trifluoroacetic acidHCID 86760563HCID 86760563, compound

Product 1

HCID 58980940HCID 58980940, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

This compound was synthesized by treating tert-butyl 5-[2-[(6-chloroquinolin-4-yl)methyl]-7-(cyclopropylmethyl)-5-methyl-4,6-dioxo-4,5,6,7-tetrahydro-2H-pyrazolo[3,4-d]pyrimidin-3-yl]4-methyl-1,3-thiazol-2-ylcarbamate with 10% TFA in dichloromethane at room temperature for 5 hours. Mass: 508.13 (M+H).

Workup

  1. customThis compound was synthesized

Sources & evidence

ORD record
ord-d67174a840824e5da16e94678a219b4e
Source dataset
uspto-grants-2007_10
Patent number
US07285558B2

Reaction notes

Loading…