HuagongsheHuagongshe Chemistry Print Report · For research reference only
1-Methyl-1H-pyrrole-2-carbaldehyde → 2-(1-benzothien-3-ylmethyl)-7-isobutyl-3-(1-methyl-1H-pyrrol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 1-Methyl-1H-pyrrole-2-carbaldehyde | HCID 14504 | — |
| Reactant | 1-Benzothiophene-3-carbaldehyde | HCID 227328 | — |
| Reactant | 6-hydrazino-1-isobutylpyrimidine-2,4(1H,3H)-dione | HCID 69428077 | — |
| Product | 2-(1-benzothien-3-ylmethyl)-7-isobutyl-3-(1-methyl-1H-pyrrol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione | HCID 69427155 | — |
Reaction Steps
This compound was isolated as a byproduct from a two step preparation as described: A): 2-(1-benzothien-3-ylmethyl)-7-isobutyl-3-(1-methyl-1H-pyrrol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione was prepared starting from 6-hydrazino-1-isobutylpyrimidine-2,4(1H,3H)-dione and condensing first with 1-benzothiophene-3-carbaldehyde, followed by 1-methyl-1H-pyrrole-2-carbaldehyde.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07285558B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-15e32caa897b44848a833d3243fdcb31 |
| Source note | uspto-grants-2007_10 |