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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1181821Generated: October 31, 2026

1-Methyl-1H-pyrrole-2-carbaldehyde → 2-(1-benzothien-3-ylmethyl)-7-isobutyl-3-(1-methyl-1H-pyrrol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

https://huagongshe.com/reaction/1181821

Reaction equation

Participants

RoleNameHCIDCharge
Reactant1-Methyl-1H-pyrrole-2-carbaldehydeHCID 14504—
Reactant1-Benzothiophene-3-carbaldehydeHCID 227328—
Reactant6-hydrazino-1-isobutylpyrimidine-2,4(1H,3H)-dioneHCID 69428077—
Product2-(1-benzothien-3-ylmethyl)-7-isobutyl-3-(1-methyl-1H-pyrrol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dioneHCID 69427155—

Reaction Steps

This compound was isolated as a byproduct from a two step preparation as described: A): 2-(1-benzothien-3-ylmethyl)-7-isobutyl-3-(1-methyl-1H-pyrrol-2-yl)-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione was prepared starting from 6-hydrazino-1-isobutylpyrimidine-2,4(1H,3H)-dione and condensing first with 1-benzothiophene-3-carbaldehyde, followed by 1-methyl-1H-pyrrole-2-carbaldehyde.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07285558B2
Source datasetuspto-grants-2007_10
ORD IDord-15e32caa897b44848a833d3243fdcb31
Source noteuspto-grants-2007_10