1-Methyl-1H-pyrrole-2-carbaldehyde → 7-(cyclopropylmethyl)-5-methyl-3-(1-methyl-1H-pyrrol-2-yl)-2-{[5-(trifluoromethyl)-1H-indol-3-yl]methyl}-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione

Participants

Role	Name	HCID	Charge
Reactant	1-Methyl-1H-pyrrole-2-carbaldehyde	HCID 14504	—
Reactant	5-(Trifluoromethyl)-1h-indole-3-carbaldehyde	HCID 28984879	—
Reactant	1-(cyclopropylmethyl)-6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione	HCID 69427171	—
Product	7-(cyclopropylmethyl)-5-methyl-3-(1-methyl-1H-pyrrol-2-yl)-2-{[5-(trifluoromethyl)-1H-indol-3-yl]methyl}-2H-pyrazolo[3,4-d]pyrimidine-4,6(5H,7H)-dione	HCID 58980954	—

Reaction Steps

This compound was made following the procedure described above, starting with 1-(cyclopropylmethyl)-6-hydrazino-3-methylpyrimidine-2,4(1H,3H)-dione, and condensing first with 5-(trifluoromethyl)-1H-indole-3-carbaldehyde, followed by 1-methyl-1H-pyrrole-2-carbaldehyde. 497.2 (M+H).

Provenance & Evidence

DOI	10.6084/m9.figshare.5104873.v1
Patent number	US07285558B2
Source dataset	uspto-grants-2007_10
ORD ID	ord-f346a423e3de4d4385558a80929cc4a2
Source note	uspto-grants-2007_10