2-Hexanol → 2-Hexyl 5-amino-4-oxopentanoate Hydrochloride

HRID 1181996Notes

Reaction equation

HRID 1181996 reaction equation
[CH3:1][CH:2]([OH:7])[CH2:3][CH2:4][CH2:5][CH3:6].[ClH:8].[NH2:9][CH2:10][C:11](=[O:17])[CH2:12][CH2:13][C:14](O)=[O:15]>>[ClH:8].[NH2:9][CH2:10][C:11](=[O:17])[CH2:12][CH2:13][C:14]([O:7][CH:2]([CH2:3][CH2:4][CH2:5][CH3:6])[CH3:1])=[O:15]

Participants

3

Reactant 2

HCID 122972-HexanolHCID 123608Aminolevulinic Acid Hydrochloride

Product 1

HCID 574382502-Hexyl 5-amino-4-oxopentanoate Hydrochloride

Procedure

From 2-hexanol (6.0 ml) and 5-amino-4-oxopentanoic acid hydrochloride (1.0 g; 6.0 mmol) at 70° C. The reaction was complete after ca. 4 h. The yield was 1.0 g (66%).

Workup

  1. customat 70° C

Sources & evidence

ORD record
ord-2c3924cd48e94252919ff6c6b79f9325
Source dataset
uspto-grants-2007_10
Patent number
US07287646B2

Reaction notes

Loading…