HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1182024Generated: October 25, 2026
2-Methoxybenzaldehyde → (2-Methoxyphenyl)(4-methoxyphenyl)methanol
https://huagongshe.com/reaction/1182024
Participants
| Role | Name | HCID | Charge |
|---|
| Reactant | 2-Methoxybenzaldehyde | HCID 8658 | — |
| Reactant | Ammonium Chloride | HCID 25517 | — |
| Reactant | HCID 178491912 | HCID 178491912 | — |
| Solvent | Tetrahydrofuran | HCID 8028 | — |
| Product | (2-Methoxyphenyl)(4-methoxyphenyl)methanol | HCID 3811722 | — |
Reaction Steps
1.5 g of o-anisaldehyde are dissolved in THF and cooled to 0° C. 24.2 ml of 4-methoxyphenylmagnesium bromide (0.5 M in THF) are added to the mixture. The reaction solution is stirred at room temperature overnight and then poured into a 20% NH4Cl solution and extracted with ethyl acetate. 2.63 g of the product are obtained, and this can be employed without further purification.C15H16O3 (244.29) MS (ESI+) 227.05 (M−OH)+
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| Patent number | US07288528B2 |
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| Source dataset | uspto-grants-2007_10 |
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| ORD ID | ord-a73e953161f34e079d4e087595bcd38b |
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| Source note | uspto-grants-2007_10 |
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