HuagongsheHuagongshe Chemistry Print Report · For research reference only
Sodium Sulfite → 2,4'-Dimethoxybenzophenone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Sodium Sulfite | HCID 24437 | — |
| Reactant | Triacetoxyperiodinane | HCID 159087 | — |
| Reactant | Sodium Bicarbonate | HCID 516892 | — |
| Reactant | (2-Methoxyphenyl)(4-methoxyphenyl)methanol | HCID 3811722 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | 2,4'-Dimethoxybenzophenone | HCID 226205 | 100.1% |
Reaction Steps
2.63 g of (4-methoxyphenyl)(2-methoxyphenyl)methanol 51 are dissolved in dichloromethane, and 5.03 g of Dess-Martin reagent are added. The mixture is stirred at room temperature for 2 h. Then 20% Na2SO3 and NaHCO3 solution are added, and the mixture is extracted with diethyl ether. The organic phase is extracted with saturated NaCl solution and dried over sodium sulfate. The solution is concentrated in vacuo and purified by column filtration. 2.61 g of 52 are obtained. C15H14O3 (242.28) MS (ESI+) 243.04 (M+H+)
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US07288528B2 |
| Source dataset | uspto-grants-2007_10 |
| ORD ID | ord-d5b41e164866415f84193b15cf2b9d31 |
| Source note | uspto-grants-2007_10 |