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HRID1182036

反应详情

EQUATION

反应方程式

HRID 1182036 的结构方程式

REACTANTS

反应物

3
结构：O=C(O)C(F)(F)F
HCID6422

未命名化合物

结构：CC(C)(C)OC(=O)[C@@H](N)CC(N)=O.Cl
HCID16218498

tert-Butyl L-asparaginate--hydrogen chloride (1/1)

C8H17ClN2O3

结构：Cc1ccc(S(=O)(=O)N2CCC[C@H]2C(=O)O)cc1.O
HCID69463844

未命名化合物

PRODUCTS

生成物

1
结构：Cc1ccc(S(=O)(=O)N2CCC[C@H]2C(=O)N[C@@H](CC(N)=O)C(=O)O)cc1
HCID9951963

未命名化合物

AUXILIARIES

试剂、催化剂与溶剂

1
结构：ClCCl
溶剂HCID6344

Dichloromethane

CH2Cl2

PROCEDURE

实验过程

N-(Toluene-4-sulfonyl)-L-proline hydrate was coupled to L-asparagine tert-butyl ester hydrochloride using the procedure described in Method 3. The title compound was prepared, via cleavage of the tert-butyl ester using trifluoroacetic acid in CH2Cl2, to provide a solid, mp=178-180° C.

WORKUP

后处理

  1. customto provide a solid, mp=178-180° C.