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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1182272Generated: November 1, 2026

HCID 11372828, compound → HCID 11189454, compound

https://huagongshe.com/reaction/1182272

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 11372828HCID 11372828—
ReactantHCID 18440025HCID 18440025—
ReactantHCID 18440052HCID 18440052—
ProductHCID 11189454HCID 11189454—

Reaction Steps

Compounds I-22, I-27 and I-29 can be prepared in similar manner except 5-[6-chloro-2-fluoro-3-(5-methyl-6-oxo-1,6-dihydro-pyridazin-3-ylmethyl)-phenoxy]-isophthalonitrile was replaced with 3-chloro-5-[6-chloro-2-fluoro-3-(5-methyl-6-oxo-1,6-dihydro-pyridazin-3-ylmethyl)-phenoxy]-benzonitrile, 3-[6-chloro-2-fluoro-3-(5-methyl-6-oxo-1,6-dihydro-pyridazin-3-ylmethyl)-phenoxy]-5-difluoromethyl-benzonitrile and 3-[6-chloro-2-fluoro-3-(5-methyl-6-oxo-1,6-dihydro-pyridazin-3-ylmethyl)-phenoxy]-5-difluoromethyl-benzonitrile respectively.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS07288542B2
Source datasetuspto-grants-2007_10
ORD IDord-8d160364d9b84c40802f5387fdb2222e
Source noteuspto-grants-2007_10