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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1182679Generated: November 2, 2026

2-Phenyl-4-carboxythiazole → 4-{2-[(2-Phenyl-thiazole-4-carbonyl)-amino]-acetyl}-piperazine-1-carboxylic acid butyl ester

https://huagongshe.com/reaction/1182679

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Phenyl-4-carboxythiazoleHCID 138928—
ReactantButyl piperazine-1-carboxylateHCID 21963126—
Product4-{2-[(2-Phenyl-thiazole-4-carbonyl)-amino]-acetyl}-piperazine-1-carboxylic acid butyl esterHCID 49764562—

Reaction Steps

This compound was prepared using a method analogous to that of Example 3, step 3.2, 2-phenyl-1.3-thiazole-4-carboxylic acid replacing intermediate 3.1 and intermediate 26.2 replacing piperazine-1-carboxylic acid butyl ester.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08664203B2
Source datasetuspto-grants-2014_03
ORD IDord-75242c61677f49de9bba78213b0c898f
Source noteuspto-grants-2014_03