HuagongsheHuagongshe Chemistry Print Report · For research reference only
2-Phenyl-4-carboxythiazole → HCID 49764818, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 2-Phenyl-4-carboxythiazole | HCID 138928 | — |
| Reactant | HCID 66651993 | HCID 66651993 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 49764818 | HCID 49764818 | — |
Reaction Steps
This compound was prepared using a method analogous to that of Example 8, step 8.3, 4-((S)-2-amino-3-methyl-butyryl)-piperazine-1-carboxylic acid butyl ester (prepared as described in WO2008044217) replacing piperazine-1-carboxylic acid butyl ester, phenyl-1,3-thiazole-4-carboxylic acid replacing intermediate 8.2 and using CH2Cl2 instead of CH2Cl2/THF. The compound was however purified by CC (EtOAc/Hept 0:1 to EtOAc/Hept 1:0).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08664203B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-e5b747c3e0a44d2a8315ea3c1e555ae6 |
| Source note | uspto-grants-2014_03 |