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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1182682Generated: November 2, 2026

HCID 45140546, compound → 4-{(S)-2-[(5-Bromo-4-phenyl-thiazole-2-carbonyl)-amino]-4-tert-butoxycarbonyl-butyryl}-piperazine-1-carboxylic acid butyl ester

https://huagongshe.com/reaction/1182682

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 45140546HCID 45140546—
Reactant5-Bromo-4-phenylthiazole-2-carboxylic acidHCID 66770121—
Product4-{(S)-2-[(5-Bromo-4-phenyl-thiazole-2-carbonyl)-amino]-4-tert-butoxycarbonyl-butyryl}-piperazine-1-carboxylic acid butyl esterHCID 66771807—

Reaction Steps

This compound was prepared using a method analogous to that of Example 8, step 8.5, intermediate 48.3 replacing 5-bromo-4-phenyl-thiazole-2-carboxylic acid and (S)-4-(2-amino-4-tert-butoxycarbonyl-butyryl)-piperazine-1-carboxylic acid butyl ester replacing intermediate 8.4.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08664203B2
Source datasetuspto-grants-2014_03
ORD IDord-0e0040061bf441e9a8a07973c85a197f
Source noteuspto-grants-2014_03