Piperazine → HCID 66863934, compound

Participants

Reaction Steps

5.1 g (15.6 mmol) 7-bromo-2-chloro-4-ethoxy-5H-pyrimido[5,4-b]indole and 13.4 g (155.8 mmol) piperazine were heated in 80 ml mesitylene to 150° C. for 7.5 h. Then, the solvent was removed and the residue was suspended in water and sucked off. 5.8 g (99%) of the title substance was obtained. ESI-MS [m/z]: 376, 378 [M+H]+

Provenance & Evidence