反应详情

200 mg (0.55 mmol) 7-bromo-2-chloro-4-(piperazin-1-yl)-5H-pyrimido[5,4-b]indole and 1.64 ml (1.64 mmol) 1 M NaOEt solution (EtOH) in 6 ml EtOH were heated in a microwave oven to 130° C. for 3 h. Then, the solvent was removed and the residue was suspended in water and sucked off. 200 mg (97%) of the title substance was obtained. ESI-MS [m/z]: 376, 378 [M+H]+

1. customThen, the solvent was removed
2. custom200 mg (97%) of the title substance was obtained