HuagongsheHuagongshe Chemistry Print Report · For research reference only
4-Piperidyloxyamine dihydrochloride → HCID 87573665, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 4-Piperidyloxyamine dihydrochloride | HCID 10313449 | — |
| Reactant | 4,4-Dimethyl-6alpha-hydroxymethyl-7alpha,17beta-dihydroxyandrostan-3-one | HCID 68730814 | — |
| Solvent | Pyridine | HCID 1049 | — |
| Product | HCID 87573665 | HCID 87573665 | — |
Reaction Steps
4,4-Dimethyl-6α-hydroxymethyl-7α,17β-dihydroxyandrostan-3-one (Preparation 10, 40 mg) and 4-piperidyloxyamine dihydrochloride (Preparation 16, 52 mg) were dissolved in pyridine (1.0 ml) and stirred at RT for 4 days. After evaporation of the solvent, the resulting solid was triturated with DCM/AcOEt 1/1 to give, after filtration, the title compound (40 mg, 86%).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08664210B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-dcd5da7b271d47d58976b96fffa7d379 |
| Source note | uspto-grants-2014_03 |