Triethylamine → HCID 86623591, compound

HRID 1182914Notes

Reaction equation

HRID 1182914 reaction equation
[F:1][CH:2]([F:16])[O:3][C:4]1[C:13]2[C:8](=[CH:9][CH:10]=[CH:11][CH:12]=2)[C:7]([CH2:14][OH:15])=[CH:6][CH:5]=1.[CH3:17][S:18](Cl)(=[O:20])=[O:19].C(N(CC)CC)C>C(Cl)Cl>[CH3:17][S:18]([O:15][CH2:14][C:7]1[C:8]2[C:13](=[CH:12][CH:11]=[CH:10][CH:9]=2)[C:4]([O:3][CH:2]([F:16])[F:1])=[CH:5][CH:6]=1)(=[O:20])=[O:19]

Participants

5

Reactant 3

HCID 8471TriethylamineHCID 31297Methanesulfonyl chlorideHCID 57514564HCID 57514564, compound

Product 1

HCID 86623591HCID 86623591, compound

Reagents, catalysts & solvents 1

HCID 6344DichloromethaneSolvent

Procedure

Prepared by reacting (4-difluoromethoxy-naphthalen-1-yl)-methanol with methanesulphonic acid chloride in methylene chloride in the presence of triethylamine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-11fdbf73736145878f803815f2eed9b1
Source dataset
uspto-grants-2014_03
Patent number
US08664232B2

Reaction notes

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