Potassium Cation → 3'-Fluoro-4'-hydroxy[1,1'-biphenyl]-4-carbonitrile

HRID 118306Notes

Reaction equation

HRID 118306 reaction equation
[Br:12][c:13]1[cH:14][c:15]([F:20])[c:16]([OH:19])[cH:17][cH:18]1.[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6]([B:9]([OH:10])[OH:11])[cH:7][cH:8]1.[CH:29]([OH:30])([CH3:31])[CH3:32].[K+:26].[K+:27].[K+:28].[OH2:33].[P:21]([O-:22])([O-:23])([O-:24])=[O:25]>>[C:1](#[N:2])[c:3]1[cH:4][cH:5][c:6](-[c:13]2[cH:14][c:15]([F:20])[c:16]([OH:19])[cH:17][cH:18]2)[cH:7][cH:8]1

Participants

7

Reactant 6

HCID 813Potassium Cation3×HCID 962WaterHCID 1061PhosphateHCID 3776IsopropanolHCID 27249814-Bromo-2-fluorophenolHCID 27343264-Cyanophenylboronic acid

Product 1

HCID 222745023'-Fluoro-4'-hydroxy[1,1'-biphenyl]-4-carbonitrile

Sources & evidence

ORD record
ord-c91852eddf10457e979dbb58fd78a858
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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