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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1183129Generated: October 30, 2026

Water → HCID 86615228, compound

https://huagongshe.com/reaction/1183129

Reaction equation

Participants

RoleNameHCIDCharge
ReactantWaterHCID 962—
ReactantLithium hydroxide, monohydrateHCID 168937—
ReactantHCID 54753949HCID 54753949—
SolventMethanolHCID 887—
ProductHCID 86615228HCID 8661522885.8%

Reaction Steps

A solution of (S)-4-tert-butoxycarbonylamino-2-hydroxybutyric acid methyl ester (1.52 g, 6.52 mmol) in methanol (20.0 mL) was treated with lithium hydroxide monohydrate (273.8 mg, 6.52 mmol) and water (2.0 mL) for 30 min, concentrated, and dried under vacuum to give a white solid (1.26 g)

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08664242B2
Source datasetuspto-grants-2014_03
ORD IDord-f529bf4a32484e3ab191bda420c7a0a2
Source noteuspto-grants-2014_03