HCID 67362336, compound → HCID 67363334, compound

Participants

Reaction Conditions

Reaction Steps

The crude methyl 1-(2-fluoro-phenyl)-5-isopropoxy-1H-pyrazole-3-carboxylate obtained in step 1 was dissolved in 6 ml of MOH, 2 ml of an aqueous 1 M solution of sodium hydroxide were added, and the mixture was stirred for 5 h at 40° C. The solvent was removed and the residue subjected to acidic aqueous work-up to give 70% of the title compound.

Provenance & Evidence