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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1183351Generated: October 26, 2026

5-(4-Bromophenyl)-3-methylisoxazol-4-amine → [5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-{1-methyl-2-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-ethyl}-amine

https://huagongshe.com/reaction/1183351

Reaction equation

Participants

RoleNameHCIDCharge
Reactant5-(4-Bromophenyl)-3-methylisoxazol-4-amineHCID 58218537—
Reactant1-[4-(4-Trifluoromethyl-benzyloxy)-phenyl]-propan-2-oneHCID 66577653—
Product[5-(4-Bromo-phenyl)-3-methyl-isoxazol-4-yl]-{1-methyl-2-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-ethyl}-amineHCID 66577685—

Reaction Steps

Prepared according to the procedure described in Example 36, Step 2, using 5-(4-bromo-phenyl)-3-methyl-isoxazol-4-ylamine and 1-[4-(4-trifluoromethyl-benzyloxy)-phenyl]-propan-2-one.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08664220B2
Source datasetuspto-grants-2014_03
ORD IDord-8dac7202b14e4296ad430bc928f326ae
Source noteuspto-grants-2014_03