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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1183362Generated: October 25, 2026

4-(2-Ethoxycarbonylethyl)benzeneboronic acid → 3-(4'-{4-[(1-Benzyl-1H-[1,2,3]triazol-4-yl)-hydroxy-methyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-propionic acid ethyl ester

https://huagongshe.com/reaction/1183362

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Ethoxycarbonylethyl)benzeneboronic acidHCID 3851700—
ReactantHCID 66579249HCID 66579249—
Product3-(4'-{4-[(1-Benzyl-1H-[1,2,3]triazol-4-yl)-hydroxy-methyl]-3-methyl-isoxazol-5-yl}-biphenyl-4-yl)-propionic acid ethyl esterHCID 66579387—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 10, using (1-benzyl-1H-[1,2,3]triazol-4-yl)-[5-(4-bromo-phenyl)-3-methyl-isoxazol-4-yl]-methanol and [4-(2-ethoxycarbonylethyl)phenyl]boronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08664220B2
Source datasetuspto-grants-2014_03
ORD IDord-b989d9a3b07b429385b807b7fe418099
Source noteuspto-grants-2014_03