Back
HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1183366Generated: October 25, 2026

4-(2-Ethoxycarbonylethyl)benzeneboronic acid → 3-[4'-(4-Formyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-propionic acid ethyl ester

https://huagongshe.com/reaction/1183366

Reaction equation

Participants

RoleNameHCIDCharge
Reactant4-(2-Ethoxycarbonylethyl)benzeneboronic acidHCID 3851700—
Reactant5-(4-Bromo-phenyl)-3-methyl-isoxazole-4-carbaldehydeHCID 82133792—
Product3-[4'-(4-Formyl-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-propionic acid ethyl esterHCID 86679093—

Reaction Steps

Prepared according to the procedure described in Example 1, Step 10, using 5-(4-bromo-phenyl)-3-methyl-isoxazole-4-carbaldehyde and [4-(2-ethoxycarbonylethyl)phenyl]boronic acid.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08664220B2
Source datasetuspto-grants-2014_03
ORD IDord-2ff868ba139f4c8493fced233a271b2c
Source noteuspto-grants-2014_03