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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1183406Generated: November 1, 2026

2-Bromo-6-phenylpyridine → {4'-[3-Methyl-4-(6-phenyl-pyridin-2-ylamino)-isoxazol-5-yl]-biphenyl-4-yl}-acetic acid ethyl ester

https://huagongshe.com/reaction/1183406

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Bromo-6-phenylpyridineHCID 568679—
ReactantEthyl 2-(4'-(4-amino-3-methylisoxazol-5-yl)-[1,1'-biphenyl]-4-yl)acetateHCID 66577589—
Product{4'-[3-Methyl-4-(6-phenyl-pyridin-2-ylamino)-isoxazol-5-yl]-biphenyl-4-yl}-acetic acid ethyl esterHCID 66577857—

Reaction Steps

Prepared according to the procedure described in Example 68, Step 2, using [4′-(4-amino-3-methyl-isoxazol-5-yl)-biphenyl-4-yl]-acetic acid ethyl ester and 2-bromo-6-phenyl-pyridine.

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08664220B2
Source datasetuspto-grants-2014_03
ORD IDord-b32aff6327274181a6b2da83c655a29c
Source noteuspto-grants-2014_03