2,6-Dibromopyridine → 2-Bromo-6-(3-(trifluoromethyl)phenyl)pyridine

HRID 1183407Notes

Reaction equation

HRID 1183407 reaction equation
CC1(C)C(C)(C)OB([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([F:18])([F:17])[F:16])[CH:10]=2)O1.[Br:20][C:21]1[CH:26]=[CH:25][CH:24]=[C:23](Br)[N:22]=1>>[Br:20][C:21]1[CH:26]=[CH:25][CH:24]=[C:23]([C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([C:15]([F:16])([F:17])[F:18])[CH:10]=2)[N:22]=1

Participants

3

Reactant 2

HCID 122742,6-DibromopyridineHCID 27606044,4,5,5-Tetramethyl-2-[3-(trifluoromethyl)phenyl]-1,3,2-dioxaborolane

Product 1

HCID 457883772-Bromo-6-(3-(trifluoromethyl)phenyl)pyridine

Procedure

Prepared according to the procedure described in Example 42, Step 2, using 4,4,5,5-tetramethyl-2-(3-trifluoromethyl-phenyl)-[1,3,2]dioxaborolane and 2,6-dibromo-pyridine.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-bdc905c2cc0645e3acbcafa7f1f7e11a
Source dataset
uspto-grants-2014_03
Patent number
US08664220B2

Reaction notes

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