Phenylboronic Acid → 2-Bromo-6-phenylpyrazine

HRID 1183409Notes

Reaction equation

HRID 1183409 reaction equation
Br[C:2]1[CH:7]=[N:6][CH:5]=[C:4]([Br:8])[N:3]=1.[C:9]1(B(O)O)[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=1>>[Br:8][C:4]1[CH:5]=[N:6][CH:7]=[C:2]([C:9]2[CH:14]=[CH:13][CH:12]=[CH:11][CH:10]=2)[N:3]=1

Participants

3

Reactant 2

HCID 66827Phenylboronic AcidHCID 203617002,6-Dibromopyrazine

Product 1

HCID 457883272-Bromo-6-phenylpyrazine

Procedure

Prepared according to the procedure described in Example 42, Step 2, using 2,6-dibromo-pyrazine and phenylboronic acid.

Workup

  1. customPrepared

Sources & evidence

ORD record
ord-4d4ee86d8c2f429096bc8cff963b4198
Source dataset
uspto-grants-2014_03
Patent number
US08664220B2

Reaction notes

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