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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 118381Generated: October 26, 2026

Hydrochloric Acid → 5-(3,3-Difluoro-piperidin-1-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl ester

https://huagongshe.com/reaction/118381

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHydrochloric AcidHCID 313—
Reactant3,3-DifluoropiperidineHCID 2758350—
Reactanttert-Butyl 5-iodoisoindoline-2-carboxylateHCID 57753580—
Product5-(3,3-Difluoro-piperidin-1-yl)-1,3-dihydro-isoindole-2-carboxylic acid tert-butyl esterHCID 57753644—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-d9e6416cdddf465b83674172518470f5
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)