Acrylic Acid → 3-(Ethylbutoxyphosphinyl)propionic acid

HRID 1183836Notes

Reaction equation

HRID 1183836 reaction equation
[CH2:1]([P:3]([O-:9])[O:4][CH2:5][CH2:6][CH2:7][CH3:8])[CH3:2].[C:10]([OH:14])(=[O:13])[CH:11]=[CH2:12]>C1(C)C=CC=CC=1>[CH2:1]([P:3]([O:4][CH2:5][CH2:6][CH2:7][CH3:8])([CH2:12][CH2:11][C:10]([OH:14])=[O:13])=[O:9])[CH3:2]

Participants

4

Reactant 2

HCID 6581Acrylic AcidHCID 86614949Butyl ethyiphosphonite

Product 1

HCID 866566803-(Ethylbutoxyphosphinyl)propionic acidYield 91%

Reagents, catalysts & solvents 1

HCID 1140TolueneSolvent2×

Procedure

149 g (1 mol) of butyl ethylphosphonite (produced as in Example 2) and 86 g (1.2 mol) of acrylic acid in 217 g of toluene are heated to about 100° C. While stirring, 124 g of a 10% strength solution of WakoV65 in toluene are metered in. The solvent is distilled off in vacuo to leave 201 g (91% of theory) of 3-(ethylbutoxyphosphinyl)propionic acid.

Workup

  1. distillationThe solvent is distilled off in vacuo

Sources & evidence

ORD record
ord-4b0174bea32145b9965c8ad7552159b8
Source dataset
uspto-grants-2014_03
Patent number
US08664418B2

Reaction notes

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