Bicarbonate Ion → 3-amino-5-(4-chlorophenyl)thiophene-2-carboxamide

HRID 118418Notes

Reaction equation

HRID 118418 reaction equation
[C:1]([O:2][C:3](=[O:4])[NH:7][c:8]1[c:9]([C:20]([NH2:21])=[O:22])[s:10][c:11](-[c:13]2[cH:14][cH:15][c:16]([Cl:19])[cH:17][cH:18]2)[cH:12]1)([CH3:5])([CH3:6])[CH3:23].[Cl:36][CH2:37][Cl:38].[F:24][C:25]([F:26])([F:27])[C:28]([OH:29])=[O:30].[Na+:35].[O-:31][C:32]([OH:33])=[O:34]>>[NH2:7][c:8]1[c:9]([C:20]([NH2:21])=[O:22])[s:10][c:11](-[c:13]2[cH:14][cH:15][c:16]([Cl:19])[cH:17][cH:18]2)[cH:12]1

Participants

6

Reactant 5

HCID 769Bicarbonate IonHCID 923Sodium ionHCID 6344DichloromethaneHCID 6422Trifluoroacetic acidHCID 86760365HCID 86760365, compound

Product 1

HCID 27563903-amino-5-(4-chlorophenyl)thiophene-2-carboxamide

Sources & evidence

ORD record
ord-8e47bb0727a04218a913f1a9c99b6f6b
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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