Benzimidazole → Benzimidazole

HRID 1184293Notes

Reaction equation

HRID 1184293 reaction equation
[N:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[NH:3][CH:2]=1.O.O.O.O.O.O.[N+]([O-])([O-])=O.[Zn+2:20].[N+]([O-])([O-])=O.CN(C=O)C.N1C2C=CC=CC=2NC=1.CO.[Zn]>CN(C=O)C.CO>[N:1]1[C:5]2[CH:6]=[CH:7][CH:8]=[CH:9][C:4]=2[NH:3][CH:2]=1.[Zn:20]

Participants

8

Reactant 4

HCID 5798BenzimidazoleHCID 15865313Zinc nitrate hexahydrateHCID 861817341184-55-0HCID 86671701HCID 86671701, compound

Product 2

HCID 5798BenzimidazoleHCID 23994Zinc

Reagents, catalysts & solvents 2

HCID 887MethanolSolventHCID 6228DimethylformamideSolvent

Procedure

Using our nonsolvent method, nanocrystals of ZIF-7 are synthesized by first dissolving 20 mmol of benzimidazole in 50 mL DMF followed by addition of 5 mmol zinc nitrate hexahydrate dissolved in 50 mL methanol. After mixing the DMF/benzimidazole and Methanol/Zinc solutions for 1 hr under vigorous stirring, phase-pure ZIF-7 nanocrystals are formed (see expected PXRD pattern in FIG. 4). The nonsolvent method produces ZIF-7 crystals approximately 199 nm with a 5 nm standard deviation based on DLS measurements (see FIG. 5). The yield of the synthesis is 0.33 gram and 0.53 gram of crystals formed per gram of benzimidazole ligand and Zinc used, respectively.

Workup

  1. customare synthesized
  2. customare formed (
  3. customThe nonsolvent method produces ZIF-7 crystals approximately 199 nm with a 5 nm standard deviation

Sources & evidence

ORD record
ord-981cbdce54a94ed2ac8f528f0fc9da7b
Source dataset
uspto-grants-2014_03
Patent number
US08668764B2

Reaction notes

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