Formic Acid → HCID 86690134, compound

Participants

Reaction Steps

Formic acid (0.157 ml, 4.09 mmol) was added to 2,2,7-trifluoro-6-hydrazinyl-4-(prop-2-ynyl)-2H-benzo[b][1,4]oxazin-3(4H)-one (the product of Step 1.7 above, 1.0 g, 3.69 mmol) in dichloromethane at room temperature under stirring. The mixture was then stirred overnight at room temperature. The resulting precipitate was isolated over a glass filter and washed with diisopropyl either to yield 858 mg of product (>95% purity), which was used without further purification.

Provenance & Evidence