HuagongsheHuagongshe Chemistry Print Report · For research reference only
3,4-Dihydro-8-fluoro-2H-1,4-benzoxazine-2-carboxamide → Dihydro-8-chloro-2H-1,4-benzoxazine-2-carboxamide
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | 3,4-Dihydro-8-fluoro-2H-1,4-benzoxazine-2-carboxamide | HCID 67480486 | — |
| Reactant | 3,4-dihydro-8-chloro-2H-1,4-benzoxazine 2-ethyl carboxylate | HCID 86664802 | — |
| Product | Dihydro-8-chloro-2H-1,4-benzoxazine-2-carboxamide | HCID 67496535 | — |
Reaction Steps
This compound is obtained using the same experimental conditions as those used for the synthesis of intermediate 4b but replacing 3,4-dihydro-8-fluoro-2H-1,4-benzoxazine-2-ethyl carboxylate (5b) with 3,4-dihydro-8-chloro-2H-1,4-benzoxazine-2-ethyl carboxylate (5d), [73268-47-0]. The title compound of formula (4d) is obtained.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669250B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-9615b7b68524456eb0663878717bdd00 |
| Source note | uspto-grants-2014_03 |