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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 1185233Generated: October 31, 2026

HCID 86684081, compound → HCID 86684082, compound

https://huagongshe.com/reaction/1185233

Reaction equation

Participants

RoleNameHCIDCharge
ReactantHCID 86684081HCID 86684081—
CatalystPalladiumHCID 23938—
ProductHCID 86684082HCID 8668408281.5%

Reaction Steps

Following the procedure of Example 151e, and starting with 159a (300 mg, 1.83 mmol) and 10% palladium on carbon (50% wet, 60 mg) afforded 159b as a yellow liquid (200 mg, 81%). 1H NMR (500 MHz, CDCl3) δ 7.24 (s, 1H), 7.14 (t, J=58.5 Hz, 1H), 4.08 (brs, 2H).

Provenance & Evidence

DOI10.6084/m9.figshare.5104873.v1
Patent numberUS08669251B2
Source datasetuspto-grants-2014_03
ORD IDord-1b6c647cb73d4cafbf88f20125a939b1
Source noteuspto-grants-2014_03