HuagongsheHuagongshe Chemistry Print Report · For research reference only
Hydrochloric Acid → Ethyl 2-(furan-2-yl)quinoline-4-carboxylate
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Hydrochloric Acid | HCID 313 | — |
| Reactant | Toluene | HCID 1140 | — |
| Reactant | 2-(Furan-2-yl)quinoline-4-carboxylic acid | HCID 697640 | — |
| Solvent | Ethanol | HCID 702 | — |
| Product | Ethyl 2-(furan-2-yl)quinoline-4-carboxylate | HCID 27000068 | — |
Reaction Steps
To 40 ml of a saturated solution of hydrochloric acid in ethanol 2 g of 2-Furan-2-yl-quinoline-4-carboxylic acid was added and the mixture was heated to reflux for 3 h. Then, after cooling to RT, 30 ml of toluene was added and the solvents were removed under reduced pressure. The obtained crude product was pure enough for the next reaction step. Yield: 2.5 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669266B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-d5671b8c2b414fc28a2b84e0a9f1bd62 |
| Source note | uspto-grants-2014_03 |