HuagongsheHuagongshe Chemistry Print Report · For research reference only
Trifluoroacetic acid → HCID 178452373, compound
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Trifluoroacetic acid | HCID 6422 | — |
| Reactant | HCID 178452367 | HCID 178452367 | — |
| Solvent | Dichloromethane | HCID 6344 | — |
| Product | HCID 178452373 | HCID 178452373 | — |
Reaction Steps
To a solution of 739 mg 4-[(S)-2-tert-Butoxycarbonylamino-3-(1H-[1,2,3]triazol-4-yl)-propionyl]-piperazine-1-carboxylic acid butyl ester in 8 ml dichloromethane were added 1.3 ml TFA. After 12 h stirring at RT the solvents were removed and the residue was codistilled twice with toluene. Yield: 1.32 g.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US08669266B2 |
| Source dataset | uspto-grants-2014_03 |
| ORD ID | ord-4e51445d2bc94283934b95e2f2cacaab |
| Source note | uspto-grants-2014_03 |